樊亚琴，博士，副教授，硕士生导师，毕业于中国海洋大学医药学院，目前在青岛农业大学山东省食用菌重点实验室食用菌精准育种实验室工作。主要从事真菌资源开发及其重要代谢产物的分离、结构鉴定和构效关系等研究。近年来主持国家及省级自然科学基金3项，参与国家重点研发计划青年项目1项，国家自然科学基金3项。以第一作者在Nat. Prod. Rep., Org. Lett.、Org. Chem. Front.、J. Org. Chem.、J. Nat. Prod.、Mar. Drugs.等杂志上发表论文16篇，授权发明专利2项。兼任中国微生物学会会员，山东省科技特派员，山东省农学会兼职科级秘书，《中国抗生素杂志》青年编委，《Food & Medicine Homology》青年编委。

1. 学术型硕士：生物学

2. 专业型硕士：生物与医药

1. 通讯地址：山东省青岛市城阳区长城路700号青岛农业大学生命科学学院/科技楼6033

2. 电子邮件：fanyaqin@qau.edu.cn

2016-09至2019-06，中国海洋大学，医药学院药物化学，博士。

2013-07至2016-08，国家海洋局第一海洋研究所，科研助理。

2010-09至2013-06，中国海洋大学，医药学院药物化学，硕士。

2006-09至2010-06，青岛科技大学，化学与分子工程学院，学士。

1、基于氧调节策略的超深渊耐低氧真菌中促血管生成活性次级代谢产物研究, 国家自然科学基金委员会, 青年项目, 42006096, 2021-01至2023.12，24万元, 主持。

2、基于酸诱导策略的红树林耐酸真菌次级代谢产物化学多样性及其群体感应抑制活性研究，山东省自然科学基金委员会，青年项目，ZR201910240193， 2021-01至2023.12，15万元, 主持。

3、雅浦海沟超深渊耐低氧真菌次级代谢产物化学多样性及促血管生成活性研究，中国博士后科学基金委员会，面上资助， 2020-07至2022-06，15万元, 主持。

4、深海药物先导化合物心血管保护活性评价新技术研究，国家重点研发计划“深海和极地关键技术与装备”重点专项，2022.11-2025.10, 200万元，任务负责人。

5、海洋微生物化学空间的拓展与抗癌先导化合物的高效发现，国家自然科学基金委员会, 联合基金项目, U1906213， 2019-01至2022-12，247万元, 参与。

6、南极磷虾微生物中氟代天然产物的发现与活性研究，国家自然科学基金委员会, 面上项目, 41876172， 2018-01至2021-12，62万元, 参与。

7、具有抗病毒作用的红树林耐酸微生物次生代谢产物的研究，国家自然科学基金委员会, 面上项目, 81373298， 2013-01至2016-12，60万元, 参与。

Yaqin Fan, Jingjing Shen, Zhi Liu, Kunyu Xia, Weiming Zhu and Peng Fu. Methylene-bridged dimeric natural products involving one-carbon unit in biosynthesis. Natural Product Reports. 2022, 39, 1305. (SCI, 1区, Top)

Yaqin Fan, Chunjiao Jiang, Peihai Li, Cong Wang, Hao Chen. A new chloro-azaphilone derivative with pro-angiogenesis activity from the hadal trench-derived fungus Chaetomium globosum YP-106. Journal of Oceanology and Limnology, 2023, 41, 1145-1151. (SCI, 2区)

Zhang Yan., Zhou Jiabao, Yang Shuting., Liu Xin, Cao Wei, Li Peihai, Chen Hao., Yaqin Fan. Anti-Inflammatory and proangiogenic metabolites from the hadal trench-derived fungus Acremonium dichromosporum YP-213. Marine drugs, 2024, 22, 25. (SCI, 2区)

Yaqin Fan, Zhiheng Ma 1, Yan Zhang, Yufei Wang, Yousong Ding, Cong Wang 2 and Shugeng Cao. Sulfur-Containing Compounds from Endophytic Fungi:Sources, Structures and Bioactivities. Journal of Fungi. 2022, 8, 628. (SCI, 2区)

Yaqin Fan, Chunjiao Jiang, Yan Zhang, Zhiheng Ma, Peihai Li, Lizhong Guo, Ting Feng, Liman Zhou, Lili Xu. Pro-angiogenic new chloro-azaphilone derivatives from the hadal trench-derived fungus Chaetomium globosum YP-106. Frontiers in Microbiology. 2022, 13, 943452. (SCI, 2区)

Chunjiao Jiang, Jiancheng Ji, Peihai Li, Wenfeng Liu, Hao Yu, Xiuqing Yang, Lili Xu, Lizhong Guo, Yaqin Fan (通讯). New lanostane-type triterpenoids with proangiogenic activity from the fruiting body of Ganoderma applanatum. Natural Product Research, 2021, 36, 1529-1535. (SCI, 3区)

Yaqin Fan, Yi Wang, Peng Fu, Arthit Chairoungdua, Pawinee Piyachaturawat, Weiming Zhu(*). Secopaxilline A, an indole-diterpenoid derivative from an aciduric Penicillium fungus, its identification and semisynthesis. Organic Chemistry Frontiers, 2018, 5, 2835-2839. (SCI, 1区, Top)

Jingjing Shen, Yaqin Fan(共同一作), Guoliang Zhu, Hao Chen, Weiming Zhu, Peng Fu. Polycyclic macrolactams generated via intramolecular diels-alder reactions from an antarctic Streptomyces species. Organic Letters, 2019, 21, 4816-4820. (SCI, 1区, Top)

Qianqian Lv, Yaqin Fan(共同一作), Ganzheng Tao, Peng Fu, Jingxin Zhai, Boping Ye, Weiming Zhu. Sekgranaticin, a SEK34b-granaticin hybrid polyketide from Streptomyces sp. 166#. Journal of Organic Chemistry, 2019, 84, 9087-9092. (SCI, 2区, Top)

Yaqin Fan, Yalin Zhou, Yuqi Du, Yi Wang, Peng Fu, Weiming Zhu. Circumdatin-aspyrone conjugates from the coral-associated Aspergillus ochraceus LCJ11-102. Marine Drugs, 2019, 17, 400. (SCI, 2区)

Hao Yu, Shuxue Zhao, Yaqin Fan(共同一作), Chunhui Hu, Weidong Lu, Lizhong Guo(*). Cloning and heterologous expression of a novel halo/alkali-stable multi-domain xylanase (XylM18) from a marine bacterium Marinimicrobium sp. strain LS-A18. Applied Microbiology and Biotechnology, 2019,103, 8899-8909. (SCI, 2区)

Yaqin Fan, Cong Wang, Liping Wang, Arthit Chairoungdua, Pawinee Piyachaturawat, Peng Fu, Weiming Zhu. New ansamycins from the deep-sea-derived bacterium Ochrobactrum sp. OUCMDZ-2164. Marine Drugs, 2018, 16, 282. (SCI, 2区)

Yaqin Fan, Guoliang Zhu, Yi Wang, Xiaocui Zhu, Qianhong Gong, Qian Jia, Peng Fu, Weiming Zhu. alpha-Pyronoids with quorum sensing inhibitory activity from the mangrove fungus Penicillium camemberti OUCMDZ-1492. Chinese Journal of Organic Chemistry, 2018, 38, 2798-2804. (SCI, 3区)

Peihai Li, Yaqin Fan(共同一作), Hao Chen, Yaxi Chao, Ning Du, Junhui Chen. Phenylquinolinones with anti-tumor activity from the Indian Ocean derived fungus Aspergillus versicolor Y31-2. Journal of Oceanology and Limnology, 2016, 34, 1072-1075. (SCI, 2区)

Yaqin Fan, Peihai Li, Yaxi Chao, Hao Chen, Ning Du, Qiuxia He and Kechun Liu. Alkaloids with cardiovascular effects from the marine-derived fungus Penicillium expansum Y32. Marine Drugs, 2015, 13, 6489-6504. (SCI, 2区)

Yaqin Fan, Yi Wang, Peipei Liu, Peng Fu, Tonghan Zhu, Wei Wang, Weiming Zhu. Anti-H1N1 Active Indole-diterpenoids from the Aciduric Fungus Penicillium camemberti OUCMDZ-1492. Journal of Natural Products, 2013, 76, 1328-1336. (SCI, 2区)

1. 樊亚琴, 张燕, 邱钰婷, 曹薇, 周家宝, 黄桂安. 化合物chaetomugilin O在制备预防或治疗甲状腺癌药物中的新用途. 授权日：2024.3.5. 专利号：ZL 2022 1 1667508.8.
2. 陈颢、樊亚琴、李培海、晁雅熙、张学雷. 具有抗心律失调活性的化合物communesin I及其制备方法和用途. 授权公告日：2017.5.3. 专利号201510653555.0。